Don't miss a second of Independiente Medellin versus Independiente Santa Fe in the Colombia. Serie A! Scheduled for Tuesday, October 6, 2026 at 02:00, this clash at Home Arena in Germany has all the ingredients for a classic. Referee Harm Osmers takes charge. Forecast: Cool and dry, 12°C. Key absences: Zimmermann (Independiente Medellin), Hoffmann (Independiente Santa Fe). These two have a storied rivalry: Independiente Medellin 3 - 2 Independiente Santa Fe (2023). Independiente Medellin 1 - 0 Independiente Santa Fe (2021). Independiente Medellin 0 - 0 Independiente Santa Fe (2023). Independiente Medellin 3 - 3 Independiente Santa Fe (2021). Independiente Medellin 3 - 0 Independiente Santa Fe (2022). Our prediction stands at 3:2.